CATALYTIC PYROLYSIS OF DISCARDED COVID-19 MASKS OVER SEPIOLITE

This research aims to develop a new strategy to valorize wasted COVID-19 masks based on pyrolysis to convert them into useful products. First, surgical and FFP2 masks were thermally pyrolyzed at temperatures of 450–550 ºC with the purpose of determining gas, liquid (oil) and solid (char) yields. At low temperatures, solid yield was high, while at high temperatures the gas product was enhanced. The highest yield of liquid was found at an operating temperature of 500 ºC in both surgical and FPP2 masks pyrolysis. The liquid product yields were 59.08% and 58.86%, respectively. Then, the volatiles generated during thermal pyrolysis of residual masks were cracked over sepiolite as catalyst at a temperature of 500 ºC. The catalytic pyrolysis increased the yield of gas product (43.89% against 39.52% for surgical masks and 50.53% against 39.41% for FFP2 masks) and decreased the viscosity of the liquid product. Finally, the effect of sepiolite regeneration and reuse in consecutive pyrolysis tests was examined. Results showed that, with the higher regeneration-reuse of sepiolite, the catalyst was degraded obtaining a liquid product with higher molecular mass. This effect was hardly noticeable in the case of FFP2 masks. © 2022 International Multidisciplinary Scientific Geoconference. All rights reserved.

Crowdfunding platforms: a systematic literature review and a bibliometric analysis

Due to the financial crisis caused by the COVID-19 pandemic, entrepreneurs and small businesses have had multiple difficulties accessing conventional types of financing. Crowdfunding platforms have gained popularity as an alternative means of online financing. The main objective of this research is to analyze the most important articles that may influence future studies on crowdfunding platforms in Latin America. This article analyzes the Scopus and Web of Science databases considering three of the four categories of crowdfunding based on capital flows: Reward, Equity, and Lending, using a systematic review of the literature and bibliometric analysis. This research resulted in a total of 1032 articles which, after applying the appropriate criteria, resulted in 55 selected articles. The results show that the number of studies conducted in the field of crowdfunding platforms is increasing. Crowdfunding platforms provide a great opportunity for entrepreneurs to obtain alternative financing and a new way for investors to invest their capital. Future lines of research include conducting studies that involve a stronger focus on the technology used in crowdfunding platforms. With systematized access to information, the different actors can understand how the dynamics of crowdfunding platforms can stimulate the development of business projects, as well as the decision-making factor when investing. This document is of great interest to researchers and professionals who wish to increase their knowledge of crowdfunding platforms, especially those of Reward, Equity, and Lending, in addition to gaining knowledge on relevant conclusions and suggestions for future research. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Community pharmacy experience in SARS-CoV-2 antigen detection testing programs

BACKGROUND: SARS-CoV-2 infection was an unprecedented pandemic with unprecedented global health and socio-economic impact. More than 13 million cases had been confirmed in Spain by August 2022, and diagnostic testing to detect cases of infection in the country has helped to partially mitigate the spread of the virus. In 2021, the first self-testing antigen tests were marketed for dispensing in community pharmacies, and over-the-counter dispensing was allowed from July of that year. The network of community pharmacies played a key role, not only in the informed dispensing of these tests, but also in actively participating in the performance, supervision and reporting of results to the health authorities, and even in the issuing of digital certificates. A compilation has been made of all the available data on the subject, with a deadline of 13 February 2022, which is considered to be the end of the sixth wave of the epidemic in Spain. The results of the action taken by community pharmacies in twelve Autonomous Communities, which somehow participated in these initiatives by carrying out or supervising a total of 1,043,800 tests, from which 109,570 positive cases (10.5% of the total) were detected and reported to the National Health System, are presented in this article. Although the results are provisional, because many of the programmes are still ongoing, they are a clear demonstration of the potential that community pharmacies can play in Public Health work.

E-learning platforms and their impact on university education during the COVID-19 pandemic

The current situation caused by COVID-19 has accelerated the change in lifestyles and therefore Universities have had to modify their teaching-learning models. The objective of this work is to explore the factors that affect the perception of satisfaction and the learning results of those when using online learning applications. Through a quantitative methodology and using as a basis the Technology Acceptance Model (TAM) and the Information Systems Success Model (ISs), the results were analyzed by means of PLS-SEM (Partial Least Squares-Structural Equation Modeling). The data were collected through a survey conducted by a structured questionnaire and sent to students of different levels of higher education. Among the main findings, it was obtained that the higher the satisfaction of users of online learning platforms, the higher the results. The information obtained can contribute to the Universities being able to enhance this type of tool to efficiently achieve the proposed educational objectives.

THE NERVOUS SYSTEM, ANOTHER VICTIM OF SARS-COV-2

COVID-19 is the name of sickness headed by SARS-CoV-2, which gated the confinement restrictions since March 2020. At the beginning the S protein was identified as the "key" that enhances entering human body, due to its affinity with ACE2 receptor. ACE2 receptor is known to be expressed in a variety of tissues in a manner in which that location increases their infection-probabilities in exposure to this virus. The brain contains two regions where ACE2 is manly expressed: 1) The olfactory bulb which is thought to be involved in loss of smell and facilitating entering to the Central Nervous System, on the other hand 2) the brainstem keeps imbibed the Pre-Botzinger complex, a mediator of respiratory rhythm, showed its implications in oxygen depletion because of abnormal working of O2, and CO2 sensing chemoreceptors. In concern with PNS it is considered virus-nociceptors interaction as the most likely reason to muscular pain and headache. © 2022 Harvard University Law School. All rights reserved.

KIR2DL2/C1: A potential predictive immunogenetic marker to COVID-19 severity in Spanish patients

COVID-19 has aspects on its pathogenesis that still need elucidating and an analysis of clinical and immunogenetic factors in each cohort of patients is paramount to understanding how genetic variability can explain the multiple clinical spectra seen in patients infected with SARS-CoV-2. The aim of this study was to correlate the KIR polymorphism/HLA class I ligand interactions from patients and healthy subjects with either the susceptibility or severity to COVID-19. Genotyping of HLA-A, -B, -C and KIR genes were carried out from 459 symptomatic as well as 667 non-infected Spanish Caucasian individuals using Lifecodes HLA-SSO and KIR-SSO kits (ImmucorTM, USA) and analyzed in the Luminex in this uni-centre case-control study performed at the University Hospital of Salamanca, Spain. Comparative KIR gene analysis showed that KIR2DS4 was significantly more representative in healthy versus infected individuals. When comparing subgroups of infected patients, KIR2DS3 had a higher frequency in those who progressed to a more severity disease and yet with higher mortality rate. Three functional combinations were significant on univariate analysis: KIR2DL2/C1, KIR2DS2/C1, and KIR2DS3/C1. However, in the multivariate analysis, only the KIR2DL2/C1 interaction remained significant (OR = 15.2 (95% CI 1.5-147), p = 0.0189). Compared with the solo-clinical characteristics predictive model, that included well-known comorbidity variables such as hypertension, age, sex, diabetes, C-reactive protein, dyslipidemia, smoking, ferritin, and fibrinogen, the clinical-and-KIR-based model showed a better ability to discriminate between severe and nonsevere patients with higher sensitivity and specificity. Our results support a fundamental role of KIR/ligand interaction in the clinical course of COVID-19. Since the KIR2DL2 gene has a high frequency in Spain (60%), the analysis of the KIR2DL2/C1 in symptomatic patients who require hospitalization could be helpful to better determine their prognosis.

Mind the Gap in Financial Inclusion! Microcredit Institutions fieldwork in Peru

Financial inclusion remains a key political issue. Since microcredit first captured public attention, Microfinance Institutions (MFIs) have expanded rapidly all around the world. Although much economic and financial literature has highlighted the importance of microfinance as a factor of development, there is also an intense debate about its effectiveness as a development tool. This paper is a descriptive analysis of the microcredit state of the art contrasted with the fieldwork done in Peru. A qualitative research methodology was used;29 in-depth face-to-face interviews were done with different microfinance agents: MFIs, NPOs, microfinance associations, and microfinance customers in Peru. Peru has been chosen because it has a dynamic and well-regulated microfinance sector with more than 70 entities specialized in microfinance. Though statistical generalization is not possible, interview data provided rich and contextual evidence, which is often missing from a quantitative research approach. This paper highlights the importance of financial and accounting education in microcredit beneficiaries and how can it be enhanced in the digital age. The COVID-19 pandemic has forced vulnerable population to embrace new digital technologies and has highlighted the digital gap that still exists in Latin America although this situation presents opportunities and challenges. This present study contributes to the debate over how to improve microcredit intervention´s impact on the more vulnerable and identifies some unique insights into the interrelationships of financial education and financial inclusion. The results of the present study confirm that financial and accounting education are key elements in financial inclusion. ©2023 ASEPUC.

Utilization of Lung Transplantation in Patients with Covid-19

Lung transplantation (LTx) had been the only survival option in selected Covid-19 infected ARDS patients. We evaluated surgical outcome in such group from multi-center ECLS study. LTx patient data (n=1488)were collected from multiple institutions through the National ECLS Registry and was stratified on presence of COVID-19 infection. LTx procedure details, patient demographics and post-operative outcomes were compared between COVID-19 and non-COVID-19 patients along with pre-op ECMO vs. no ECMO COVID-19 patients using Wilcoxon rank sum test or Chi-square testing to determine distribution. Time to 30-day post-operative survival was analyzed in combination with Kaplan-Meier survival curves with log-rank testing to assess mortality in these groups of patients. P values <0.05 were considered statistically significant. Out of 1488 LTx patients, our results included a total of 34 patients infected with COVID-19 at time of LTx. When compared between covid LTx (n=34) vs. non-covid LTx (n=1,454), demographic data revealed significant differences in tracheostomy (p=0.0001), lung allocation score (p=0.0001), type of pre-op ECMO support (p=0.0001), type of ECMO support (p=0.001), conversion (p=0.006), and ventilator support time (p=0.0001);but no significant differences in gender (p=0.30), BMI (p=0.32), EVLP (p=0.078), PGD score at T24 (p=0.13), and waitlist time (p=0.75). 30-day post-operative mortality analysis showed K-M graph with no statistical significance (p=0.41) in COVID-19 and non-COVID-19 patients. In addition, we compared pre-ECMO utilized COVID-19 patients (n=21) vs. non-ECMO utilized COVID-19 patients (n=13) who were transplanted. Covid-19 infected patients when transplanted showed no significant differences in survival. Propensity score matched study indicated similar results. Selective ARDS patients may benefit from end-stage surgical options like lung transplantation. [ FROM AUTHOR] Copyright of Journal of Heart & Lung Transplantation is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

The telework performance dilemma: exploring the role of trust, social isolation and fatigue

Purpose: Due to the crisis originated by the COVID-19 pandemic, an important number of workers have been incorporating the telework modality. In this context, the distance from the workplace generates new dilemmas for work performance. In the paper the authors study the role of some individual and social antecedents on telework outcomes. In particular, they empirically investigate the direct relationship between trust (TR) and telework performance (PER) and explore mediators of that relationship such as social isolation (SI) and fatigue (FA). Design/methodology/approach: A theoretical model with three main hypotheses is proposed and tested using partial least square structural equation modeling (PLS-SEM). The study sample, of an exploratory nature, consists of a dataset of 201 teleworkers working in Spanish companies. Findings: The relevance of the proposed model is demonstrated and FA is found to be the factor that most affects (negatively) PER, followed by TR (positively) and SI (negatively). Beyond the direct effects, the results provide support for the role of SI and FA in mediating the relationship between TR and PER. Originality/value: This paper discusses the PER dilemma and proposes and tests a background model that may be useful for future research. The results are of interest to human resource managers, consultants, academics and telework tool developers and managers. Practices are proposed to improve TR or to reduce feelings of SI or FA. The research provides a practical evaluation tool for telework implementation. © 2023, Emerald Publishing Limited.

[The experience of community pharmacy in SARS-CoV-2 antigen detection tests programs.]

SARS-CoV-2 infection was an unprecedented pandemic with unprecedented global health and socio-economic impact. More than 13 million cases had been confirmed in Spain by August 2022, and diagnostic testing to detect cases of infection in the country has helped to partially mitigate the spread of the virus. In 2021, the first self-testing antigen tests were marketed for dispensing in community pharmacies, and over-the-counter dispensing was allowed from July of that year. The network of community pharmacies played a key role, not only in the informed dispensing of these tests, but also in actively participating in the performance, supervision and reporting of results to the health authorities, and even in the issuing of digital certificates. A compilation has been made of all the available data on the subject, with a deadline of 13 February 2022, which is considered to be the end of the sixth wave of the epidemic in Spain. The results of the action taken by community pharmacies in twelve Autonomous Communities, which somehow participated in these initiatives by carrying out or supervising a total of 1,043,800 tests, from which 109,570 positive cases (10.5% of the total) were detected and reported to the National Health System, are presented in this article. Although the results are provisional, because many of the programmes are still ongoing, they are a clear demonstration of the potential that community pharmacies can play in Public Health work.

The experience of community pharmacy in SARS-CoV-2 antigen detection tests programs

SARS-CoV-2 infection was an unprecedented pandemic with unprecedented global health and socio-economic impact. More than 13 million cases had been confirmed in Spain by August 2022, and diagnostic testing to detect cases of infection in the country has helped to partially mitigate the spread of the virus. In 2021, the first self-testing antigen tests were marketed for dispensing in community pharmacies, and over-the-counter dispensing was allowed from July of that year. The network of community pharmacies played a key role, not only in the informed dispensing of these tests, but also in actively participating in the performance, supervision and reporting of results to the health authorities, and even in the issuing of digital certificates. A compilation has been made of all the available data on the subject, with a deadline of 13 February 2022, which is considered to be the end of the sixth wave of the epidemic in Spain. The results of the action taken by community pharmacies in twelve Autonomous Communities, which somehow participated in these initiatives by carrying out or supervising a total of 1,043,800 tests, from which 109,570 positive cases (10.5% of the total) were detected and reported to the National Health System, are presented in this article. Although the results are provisional, because many of the programmes are still ongoing, they are a clear demonstration of the potential that community pharmacies can play in Public Health work.;La infección por SARS-CoV-2 ha constituido una pandemia con un impacto sanitario y socioeconómico global sin precedentes. Con más de trece millones de casos confirmados en España hasta agosto de 2022, la realización de pruebas diagnósticas para detectar los casos de infección ha permitido atenuar parcialmente la expansión del virus. Durante 2021 se comercializaron los primeros test de antígenos para autodiagnóstico, de dispensación en farmacias comunitarias, y desde julio de ese año se permitió su dispensación sin receta médica. La red de farmacias comunitarias jugó un papel fundamental, no solo por la dispensación informada de dichos test, sino participando activamente en la realización, en la supervisión de su realización y en la notificación de resultados a las autoridades sanitarias, e incluso en la emisión de certificados digitales. Se ha realizado una recopilación de todos los datos disponibles al respecto, fijando como límite temporal la semana del 13 de febrero de 2022, por considerarse como el final de la sexta ola de la epidemia en España. El presente artículo revela los resultados derivados de la actuación de las farmacias de doce comunidades autónomas, que participaron de una forma u otra en dichas iniciativas mediante la realización o supervisión de un total de 1.043.800 pruebas, a partir de las cuales se detectaron 109.570 casos positivos (un 10,5% del total), que fueron comunicados al Sistema Nacional de Salud. Los resultados son provisionales, pues muchos de los programas continúan vigentes, pero son una muestra inequívoca del potencial que las farmacias comunitarias pueden desempeñar en tareas de Salud Pública.

Actions of the medicines information centre in the COVID-19 crisis

Background: The pandemic of coronavirus disease 2019 has led to a health crisis situation in which all healthcare sector have set up information mechanisms aimed at their own professionals, as well as the population. Among them, the General Pharmaceutical Council of Spain has carried out different actions to improve knowledge of the pandemic. Purpose(s): Ensuring that the General Council conveys the information to pharmacists, other health professionals and patients. Method(s): The General Council has set up a specific information centre on COVID-19, aimed at centralising the information activities carried out in this area, such as direct resolution of queries from professionals and the general public, publication of technical reports, creation of an information website, issuance of official communications or production of information videos. Result(s): Since the outbreak of the crisis, a total of 198 queries have been received;35% were from Provincial Pharmacists' Chambers, 51% from pharmacists, and 14% from other professionals and citizens. The most consulted topics were about prevention of contagion through hydroalcoholic solutions, use of masks and action procedure in community pharmacy. Conclusion(s): The General Council has positioned itself as an information reference for this health crisis management. The implementation of a landline for telephone queries and real concerns allowed the information issued to be tailored to the demands of health professionals and citizens.

[The experience of community pharmacy in SARS-CoV-2 antigen detection tests programs.]

SARS-CoV-2 infection was an unprecedented pandemic with unprecedented global health and socio-economic impact. More than 13 million cases had been confirmed in Spain by August 2022, and diagnostic testing to detect cases of infection in the country has helped to partially mitigate the spread of the virus. In 2021, the first self-testing antigen tests were marketed for dispensing in community pharmacies, and over-the-counter dispensing was allowed from July of that year. The network of community pharmacies played a key role, not only in the informed dispensing of these tests, but also in actively participating in the performance, supervision and reporting of results to the health authorities, and even in the issuing of digital certificates. A compilation has been made of all the available data on the subject, with a deadline of 13 February 2022, which is considered to be the end of the sixth wave of the epidemic in Spain. The results of the action taken by community pharmacies in twelve Autonomous Communities, which somehow participated in these initiatives by carrying out or supervising a total of 1,043,800 tests, from which 109,570 positive cases (10.5% of the total) were detected and reported to the National Health System, are presented in this article. Although the results are provisional, because many of the programmes are still ongoing, they are a clear demonstration of the potential that community pharmacies can play in Public Health work.

Mind the Gap in Financial Inclusion! Microcredit Institutions fieldwork in Peru

Financial inclusion remains a key political issue. Since microcredit first captured public attention, Microfin-ance Institutions (MFIs) have expanded rapidly all around the world. Although much economic and fin-ancial literature has highlighted the importance of microfinance as a factor of development, there is also an intense debate about its effectiveness as a development tool. This paper is a descriptive analysis of the microcredit state of the art contrasted with the fieldwork done in Peru. A qualitative research methodo-logy was used;29 in-depth face-to-face interviews were done with different microfinance agents: MFIs, NPOs, microfinance associations, and microfinance customers in Peru. Peru has been chosen because it has a dynamic and well-regulated microfinance sector with more than 70 entities specialized in microfin-ance. Though statistical generalization is not possible, interview data provided rich and contextual evidence, which is often missing from a quantitative research approach. This paper highlights the importance of fin-ancial and accounting education in microcredit beneficiaries and how can it be enhanced in the digital age. The COVID-19 pandemic has forced vulnerable population to embrace new digital technologies and has highlighted the digital gap that still exists in Latin America although this situation presents opportunities and challenges. This present study contributes to the debate over how to improve microcredit interventions ' impact on the more vulnerable and identifies some unique insights into the interrelationships of financial education and financial inclusion. The results of the present study confirm that financial and accounting education are key elements in financial inclusion. (c) 2023 ASEPUC. Published by EDITUM -Universidad de Murcia. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Shared and Specific Systemic Cytokine Responses in Infants Hospitalized with SARS-CoV-2 versus RSV Infection

Background. Cytokines play a major role in the immune response to viral infections, contributing to viral clearance but also mediating immunopathology following infection. We sought to define and compare systemic cytokine responses in infants hospitalized with COVID-19 versus RSV infection (RSVi). Methods. Prospective study of convenience cohort of infants hospitalized with PCR confirmed SARS-CoV-2 or RSVi, as well as pre-pandemic healthy controls (HC). Blood samples were obtained at enrollment and cytokine analysis performed using a 92-cytokine inflammation panel (Olink platform). Statistical analyses were performed in R environment. Results. We enrolled 26 infants with COVID-19, 77 with RSVi, and 18 healthy infants as a comparator control group. Oxygen requirement was significantly more frequent in infants with RSVi (p=0.02), while presence of comorbidities was significantly more common in infants with COVID-19 (p=0.01). No statistical differences were identified in terms of length of stay, admission to pediatric intensive care unit, need for mechanical ventilation, and lymphocyte counts (Table 1). Principal component analysis (PCA) revealed clustering of the global cytokine profiles differentiating HC from infants with COVID-19 and RSVi (Figure 1A). Multiple comparison analysis among the three groups yielded 49 significantly different cytokines clustered in three groups. A first cluster that included cytokines such as CCL11, CCL19 and TNFSF12 were lower in both COVID-19 and RSVi compared to HC;a second cluster with CCL8, CXCL8 and CASP8 that were mildly increased in both COVID-19 and RSVi;and a third cluster that included IL6, IL17C and IFN-gamma were markedly increased in both viral groups compared with HC (ANOVA padj< 0.05) (Figure 1B). Direct comparison between COVID-19 and RSVi (padj< 0.05 and FC >1.5) identified 7 statistically different cytokines. CCL8, CXCL1, CCL20 concentrations were increased in COVID-19, while SIRT2, STAMBP, MMP10 and EIF4EBP1 concentrations were increased in RSVi (Figure 1C-D). Conclusion. Analysis of systemic cytokine profiles identified shared but also distinct cytokine responses in infants with SARS-CoV-2 and RSVi suggesting important differences in the pathogenesis of these viral infections. (Figure Presented).

Mucosal Antiviral Cytokine Responses Are Impaired in Children and Adolescents with Severe COVID-19

Background. The factors associated with severe COVID-19 in pediatric patients remain poorly understood. We sought to determine whether mucosal innate immunity cytokines were associated with disease severity in children and adolescents with acute COVID-19. Methods. Single-center, prospective study including children and adolescents < 21 years of age hospitalized because of symptomatic COVID-19 from 3/2020 to 1/ 2021, and age, sex and race matched pre-pandemic (2016-2019) healthy controls. Nasopharyngeal (NP) samples were obtained at enrollment for measurement of SARS-CoV-2 viral loads by rt-PCR and cytokine concentrations using a 92-plex inflammation/ antiviral panel (Olink). Disease severity was assessed by the need for supplemental oxygen or PICU admission, and patients classified as severe and non-severe based on these two parameters. Statistical analyses were performed in R studio and Benjamini-Hochberg applied to adjust for multiple comparisons. Results. Of the 75 children with acute COVID-19 (median IQR age: 3.4 [0.2-15.3] years), 28 (37%) were classified as severe COVID-19 (19 PICU;25 supplemental oxygen) and 47 (63%) were non-severe. Children with severe COVID-19 were predominantly male and had an underlying condition more frequently than those with non-severe disease (79% vs 49% respectively;p< 0.01, Table 1). SARS-CoV-2 viral loads were comparable between groups, yet patients with severe COVID-19 had significantly higher concentrations of C-reactive protein (p=0.04), more frequent lymphopenia (p=0.03) and cardiac involvement (p=0.04), and received COVID-19 directed therapies more commonly (p< 0.001). Comparative analyses identified 24 cytokines that were significantly different between children with acute COVID-19 versus 45 healthy controls. Of those, concentrations of IFN-gamma (p=0.004), CXCL10 (p=0.01), CXCL11 (p=0.02) and CCL19 (p=0.02) were significantly lower in children with severe versus those with non-severe COVID-19 (Fig 1). Conclusion. Mucosal concentrations of antiviral/regulatory cytokines were decreased in children with severe COVID-19. These findings suggest that impaired mucosal innate immune responses might favor SARS-CoV-2 disease progression and severity in children. (Figure Presented).

The Use of New Technologies Applied to the Project-Based Learning Method in an International Context: VII Virtual Intensive Programme on the Future of Banking and Finance

The use of new technologies applied to teaching has led to a qualitative leap in education due to the pandemic caused by COVID-19. This chapter describes the experience of converting an intensive program that had been celebrated in person since 2014, into an online event. Thus, through a project-based learning process, students of different nationalities were able to expand their knowledge related to ethics and finance, as well as other skillsets, such as autonomous and collaborative work, working in a multicultural environment, or the development of technological and language skills. All this was possible thanks to recent developments in software and applications that allow students and teachers to collaborate simultaneously while being separated by hundreds of kilometers in different European cities. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

ANALYSIS OF INDICATORS TO PROMOTE SCIENTIFIC CULTURE: A DECADE OF ACTIVITY IN THE CSIC

Activities to promote Scientific Culture have be-come common practice in research institutes, which allocate financial and human resources to them. Scientific and technical staff increasingly incorporate this mission into their tradition-al research and teaching tasks. However, while research and teaching have established indicators, Scientific Culture activities are still considered unusual and are rarely recognized at an institutional level. In this sense, we believe that developing indicators for Scientific Culture would help change this situation and obtain objective data that could be used to orient social communication actions in science. The Consejo Superior de Investigaciones Científicas (CSIC), through its Deputy Vice Presidency of Scientific Culture, has proposed an analysis of the activities developed that help define appropriate Scientific Culture indicators. The CSIC has classified the Scientific Culture activity undertaken between 2011 and 2019, using the following indicators: 1) financial investment;(2) staff dedicated to Scientific Culture;(3) the number and type of activities held;and (4) the public reached. Among the main conclusions, we can highlight that the CSIC has a fairly stable critical mass of about 200 people who are dedicated to Scientific Culture endeavours. Every year around 15,000 activities are carried out (in-person and vir-tual) with the participation of around 3,000 CSIC workers. Each year more than a million and a half people attended in-person ac-tivities. 2020 will be the subject of an individualized study, as the special circumstances of the COVID-19 pandemic have made it a unique exercise with its own analysis identity. © 2022 CSIC.

Assessment of the patient safety culture in the ICU of a second level hospital at the end of the third COVID-19 wave Valoración de la cultura de seguridad del paciente en la UCI de un hospital de segundo nivel al finalizar la tercera oleada de COVID-19

Introduction Current healthcare settings and ICUs especially are complex, highly technical, and multidisciplinary, with interactions between healthcare professionals and users, in which there may be errors at different levels. Our objective was to assess the perception of patient safety in our unit at the end of the third wave of the COVID pandemic, with the intention of conducting subsequent improvement actions. Methods Observational, cross-sectional, and descriptive study. The perception of Safety Culture was estimated using the HSOPS questionnaire translated into Spanish. Some questions were posed in a positive sense, and others in a negative sense. The response was also rated as positive, negative, or neutral. Our findings were compared visually, not mathematically, with those found in the previous national study «Analysis of the culture on patient safety in the hospital setting of the Spanish National Health System» published in 2009. A subgroup analysis was performed according to professional group and seniority as a health worker. The Student's t, χ? and ANOVA tests were used. Results Sixty-two professionals responded to the questionnaire, 73.90% of the total. The median time working in ICU 2 years (interquartile range 2-4.5 years). The rating for the degree of safety was 8.06 (SD 1.16). The majority (91.20%) had not reported any adverse event in the last year. A total of 30.90% had recently received patient safety training. The dimensions considered as weaknesses were 9 («Staffing», with 27.57% of positive responses) and 10 (“Support of the hospital management in safety”, with 17.64% of positive responses). The dimensions considered as strengths were 3 («Expectation of actions by management / supervision of the service») with 85.29% of positive responses, and 5 («Teamwork») with 95.58% of positive responses. The Cronbach's alpha index values suggest that the questionnaire has adequate internal consistency. In general, our data are more positive than those collected in the 2011 national survey, although the 2 dimensions considered weaknesses were already considered such in the previous work. Conclusions The perception of patient safety in the ICU of our hospital after the end of the third wave of the COVID pandemic is adequate, with a more positive rating than that of the national study on safety culture at the hospital level carried out in 2009. The constant quest for patient safety should prioritize activity in the 2 dimensions considered weaknesses: staffing, and support from hospital management in everything related to patient safety.

Assessment of the patient safety culture in the ICU of a second level hospital at the end of the third COVID-19 wave.

INTRODUCTION: Current healthcare settings and ICUs especially are complex, highly technical, and multidisciplinary, with interactions between healthcare professionals and users, in which there may be errors at different levels. Our objective was to assess the perception of patient safety in our unit at the end of the third wave of the COVID pandemic, with the intention of conducting subsequent improvement actions. METHODS: Observational, cross-sectional, and descriptive study. The perception of Safety Culture was estimated using the HSOPS questionnaire translated into Spanish. Some questions were posed in a positive sense, and others in a negative sense. The response was also rated as positive, negative, or neutral. Our findings were compared visually, not mathematically, with those found in the previous national study «Analysis of the culture on patient safety in the hospital setting of the Spanish National Health System¼ published in 2009. A subgroup analysis was performed according to professional group and seniority as a health worker. The Student's t, χ2 and ANOVA tests were used. RESULTS: Sixty-two professionals responded to the questionnaire, 73.90% of the total. The median time working in ICU 2 years (interquartile range 2-4.5 years). The rating for the degree of safety was 8.06 (SD 1.16). The majority (91.20%) had not reported any adverse event in the last year. A total of 30.90% had recently received patient safety training. The dimensions considered as weaknesses were 9 ("Staffing", with 27.57% of positive responses) and 10 ("Support of the hospital management in safety", with 17.64% of positive responses). The dimensions considered as strengths were 3 ("Expectation of actions by management/supervision of the service") with 85.29% of positive responses, and 5 ("Teamwork") with 95.58% of positive responses. The Cronbach's alpha index values suggest that the questionnaire has adequate internal consistency. In general, our data are more positive than those collected in the 2011 national survey, although the 2 dimensions considered weaknesses were already considered such in the previous work. CONCLUSIONS: The perception of patient safety in the ICU of our hospital after the end of the third wave of the COVID pandemic is adequate, with a more positive rating than that of the national study on safety culture at the hospital level carried out in 2009. The constant quest for patient safety should prioritize activity in the 2 dimensions considered weaknesses: staffing, and support from hospital management in everything related to patient safety.